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Fingertip Health Monitoring: A Handy Solution

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September 03, 2024

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Engineers at the University of California San Diego have made a groundbreaking advancement in wearable health technology with the development of an electronic finger wrap that can monitor vital chemical levels in real-time. This innovative device is capable of analyzing key biomarkers such as glucose, vitamins, and even drugs directly from the sweat on a person's fingertip, using that same sweat to power its operations.

The research team, led by Professor Joseph Wang from the Department of Chemical and Nano Engineering at UC San Diego, recently published their findings in Nature Electronics on Sept. 3. The device, designed to snugly wrap around the finger, harnesses the abundant sweat produced by the fingertip as a source of energy. Fingertips are known to be one of the body's most active sweat glands, generating significantly more sweat than other areas, even at rest.

Constructed from flexible and stretchable polymer material, the electronic components of the device are printed onto its surface, allowing it to conform to the finger while maintaining durability against bending, stretching, and movement. Wang explained, "It is based on a remarkable integration of energy harvesting and storage components, with multiple biosensors in a fluidic microchannel, along with the corresponding electronic controller, all at the fingertip."

Central to the device's functionality are biofuel cells strategically positioned at the point of contact with the fingertip. These cells are engineered to efficiently convert the chemicals present in sweat into electricity, which is then stored in stretchable silver chloride-zinc batteries. These batteries power a set of four sensors embedded in the device, each dedicated to monitoring specific biomarkers such as glucose, vitamin C, lactate, and levodopa—a drug used in Parkinson's disease treatment.

Through a series of paper microfluidic channels, sweat is directed to the sensors for analysis, all while the device continues to draw energy from the sweat itself. The processed data is wirelessly transmitted via Bluetooth low energy to a custom smartphone or laptop application for real-time monitoring. "Autonomous power, sensing, and treatment all in one device—that's the ultimate goal," Ding, a postdoctoral researcher in Wang's group, emphasized.

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